Pharmacokinetics and Pharmacodynamics

Discussion Week 1: Pharmacokinetics and Pharmacodynamics

As an advanced practice nurse assisting physicians in the diagnosis and treatment of disorders, it is important to not only understand the impact of disorders on the body, but also the impact of drug treatments on the body. The relationships between drugs and the body can be described by pharmacokinetics and pharmacodynamics.

Pharmacokinetics describes what the body does to the drug through absorption, distribution, metabolism, and excretion, whereas pharmacodynamics describes what the drug does to the body.

When selecting drugs and determining dosages for patients, it is essential to consider individual patient factors that might impact the patient’s pharmacokinetic and pharmacodynamic processes. These patient factors include genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking, alcohol, illicit drug abuse), and/or pathophysiological changes due to disease.

For this Discussion, you reflect on a case from your past clinical experiences and consider how a patient’s pharmacokinetic and pharmacodynamic processes may alter his or her response to a drug.

To Prepare

· Review the Resources for this module and consider the principles of pharmacokinetics and pharmacodynamics. (See pdf attachments and below links)

PART 1300 – Section 1300.01 Definitions relating to controlled substances (usdoj.gov)

Mid-Level Practitioners Authorization by State (usdoj.gov)

Registration (usdoj.gov)

List of Error-Prone Abbreviations | Institute For Safe Medication Practices (ismp.org)

· Reflect on your experiences, observations, and/or clinical practices from the last 5 years and think about how pharmacokinetic and pharmacodynamic factors altered his or her anticipated response to a drug.

· Consider factors that might have influenced the patient’s pharmacokinetic and pharmacodynamic processes, such as genetics (including pharmacogenetics), gender, ethnicity, age, behavior, and/or possible pathophysiological changes due to disease.

· Think about a personalized plan of care based on these influencing factors and patient history in your case study.

Discussion – Instructions

1. Post a description of the patient case from your experiences, observations, and/or clinical practice from the last 5 years. (Please use some case related to Behavioral Health)

2. Describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of the patient you identified.

3. Explain details of the personalized plan of care that you would develop based on influencing factors and patient history in your case.

4. Be specific and provide examples.

5. Use at least 3 references. (One of them from the resources provided)

6. Review the Grading RubricPharmacodynamics

As an advanced practice nurse assisting physicians in the diagnosis and treatment of disorders, it is

important to not only understand the impact of disorders on the body, but also the impact of drug

treatments on the bod

y. The relationships between drugs and the body can be described by

pharmacokinetics and pharmacodynamics.

Pharmacokinetics describes what the body does to the drug through absorption, distribution,

metabolism, and excretion, whereas pharmacodynamics descr

ibes what the drug does to the body

.

When selecting drugs and determining dosages for patients, it is essential to consider individual

patient factors that might impact the pat

ient’s pharmacokinetic and pharmacodynamic processes.

These patient factors include genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking,

alcohol, illicit drug abuse), and/or pathophysiological changes due to disease.

For this Discuss

ion, you reflect on a case from your past clinical experiences and consider how a

patient’s pharmacokinetic and pharmacodynamic processes may alter his or her response to a drug.

To Prepare

·

Review the Resources for this module and consider the principles o

f pharmacokinetics and

pharmacodynamics.

(

See

p

df attachments a

nd

below l

inks)

PART 1300

–

Section 1300.01 Definitions relating to controlled substances (usdoj.gov)

Mid

–

Level Practitioners Authorization by State (usdoj.gov)

Registration (usdoj.gov)

List of Error

–

Prone Abbreviations | Institute For Safe Medication Practices (ismp.org)

·

Reflect on your experiences, observations, and/or clinical practices from the last 5 years and

think about how pharmacokinetic and pharmacodynamic factors altered his or her anticipated

response to a drug.

·

Consider

factors that might have influenced the patient’s pharmacokinetic and

pharmacodynamic processes, such as genetics (including pharmacogenetics), gender,

ethnicity, age, behavior, and/or possible pathophysiological changes due to disease.

·

Think about a person

alized plan of care based on these influencing factors and patient history

in your case study.

Discussion

–

Instructions

1.

Post

a description of the patient case from your experiences, observations, and/or clinical

practice from the last 5 years.

(

Please use some case related to

B

ehavioral Health

)

2.

D

escribe fac

tors that might have influenced pharmacokinetic and pharmacodynamic processes of

the patient you identified.

3.

E

xplain details of the personalized plan of care that you would develop based on influencing

factors and patient history in your case.